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Cow's Milk Protein Allergy


Nestlé Health Science: Supporting cow’s milk protein allergy diagnosis and management

Cow’s milk protein allergy (CMPA) is one of the most common food allergies in infants1 and it often presents with diverse and non-specific symptoms, making it challenging to diagnose. At Nestlé Health Science, we understand this challenge and are committed to providing expert-developed tools, nutritional solutions and support for healthcare professionals to help facilitate the earlier diagnosis and appropriate management of infants and young children with CMPA. We are also dedicated to providing information, tools and support for caregivers to help raise awareness around the symptoms of CMPA.

Signs and symptoms

Inconsolable crying, colic, skin rashes, vomiting, diarrhea, and constipation are all common signs and symptoms of CMPA, especially in early infancy.

Signs & symptoms
The CoMiSS® awareness tool is available in print and online

Consider CMPA

Leading experts have developed the Cow’s Milk-related Symptom Score (CoMiSS®) to help healthcare professionals recognize and assess non-specific signs and symptoms that could be indicative of CMPA.

CoMiSS® tool
Doctor examining an infant with suspected cow’s milk protein allergy

Clarify the diagnosis

Diagnosis of CMPA can be challenging, and few tests are available to help assess the presence of CMPA. The gold standard for diagnosing CMPA is the elimination diet, which is free from cow’s milk protein, followed by a food challenge.

Diagnosing CMPA


Nestlé Health Science has a range of nutritional solutions that are tailor-made to meet the specific needs of infants with CMPA. Our formulas are nutritionally complete to support normal growth and development in infants.
Nestlé Health Science’s

commitment to CMPA education

Nestlé Health Science is dedicated to developing and sharing leading scientific information and educational tools to support in the identification of CMPA for healthcare professionals and to help caregivers during their journey with CMPA.

Prof. Yvan Vandenplas talks about how to diagnose CMPA

Expert Corner : CMPA Diagnosis

Leading experts in paediatric gastroenterology and food allergy answer common questions related to the diagnosis of CMPA in our web series videos.

Watch now
Infant sleeping

Case studies


Understand some of the diagnostic and management challenges – from the first symptom diagnosis to the nutritional solution in a series of case studies following infants and young children with CMPA.

Read more
Mother searching for information online while baby sleeps

Support for parents and caregivers

Information and tools are available for parents to support them along their CMPA journey.

Find materials


  1. Koletzko S, et al. Diagnostic Approach and Management of Cow’s-Milk Protein Allergy in Infants and Children: ESPGHAN Gl Committee Practical Guidelines. JPGN 2012;55:221–9
IMPORTANT NOTICE: Mothers should be encouraged to continue breastfeeding even when their babies have cow’s milk protein allergy. This usually requires qualified dietary counseling to completely exclude all sources of cow’s milk protein from the mothers’ diet. If a decision to use a special formula intended for infants is taken, it is important to follow the instructions on the label. Unboiled water, unboiled bottles or incorrect dilution can make babies ill. Incorrect storage, handling, preparation and feeding can eventually lead to adverse effects on the health of babies. Formula for special medical purposes intended for infants must be used under medical supervision.